Endocrine Abstracts

Introduction: Gastrointestinal tract is one of the most affected systems in hypothyroidism. The most plausible mechanism in the pathogenesis is the development of interstitial edema subsequent to accumulation of glycosaminoglycans. Despite decreased esophageal emptying, prolonged esophageal and gastric transit time has been indicated in previous reports, the mechanism of thyroid hormones activity on the gastrointestinal system is not yet fully understood. To our knowledge, thi...